PARP7-IN-15
PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC50 of 0.56 nM, that has antitumor activity[1].
Product Specifications
CAS Number
2819998-97-3
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp7-in-15.html
Purity
98.22
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C1C(C(F)(F)F)=C(N2CC[C@H]2COCCC(N3C[C@@H](COC4=C5N=CC(C(F)(F)F)=C4)N5CC3)=O)C=NN1
Molecular Formula
C23H24F6N6O4
Molecular Weight
562.46
References & Citations
[1]Silong Zhang , et al. Exploring the structural-activity relationship of hexahydropyrazino[1,2-d]pyrido[3,2-b][1,4]oxazine derivatives as potent and orally-bioavailable PARP7 inhibitors. Eur J Med Chem. 2023 Oct 8:261:115836.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP7
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HA751323 100 µL
Phospho-RICTOR (T1135) Recombinant Rabbit monoclonal Antibody
Sign In for Pricing
View Details 
