CK1 Peptide Substrate

<strong>CK1 Peptide Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2011253_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1603.9 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Casein Kinase 1 Substrate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Jiang J. CK1 in Developmental Signaling: Hedgehog and Wnt Curr Top Dev Biol. 2017;123:303-329._x000D_ 2: Tan ST, Dai C, Liu HT, Xue HW. Arabidopsis casein kinase1 proteins CK1.3 and CK1.4 phosphorylate cryptochrome2 to regulate blue light signaling Plant Cell. 2013 Jul;25(7):2618-32._x000D_ 3: Ode KL, Ueda HR. Design Principles of Phosphorylation-Dependent Timekeeping in Eukaryotic Circadian Clocks Cold Spring Harb Perspect Biol. 2018 Aug 1;10(8):a028357._x000D_ 4: Knippschild U, Gocht A, Wolff S, Huber N, Löhler J, Stöter M. The casein kinase 1 family: participation in multiple cellular processes in eukaryotes Cell Signal. 2005 Jun;17(6):675-89._x000D_ 5: Calabokis M, Kurz L, Gonzatti MI, Bubis J. Protein kinase CK1 from Trypanosoma cruzi J Protein Chem. 2003 Aug;22(6):591-9._x000D_ 6: Philpott JM, Narasimamurthy R, Ricci CG, Freeberg AM, Hunt SR, Yee LE, Pelofsky RS, Tripathi S, Virshup DM, Partch CL. Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch Elife. 2020 Feb 11;9:e52343._x000D_ 7: Gebel J, Tuppi M, Chaikuad A, Hötte K, Schröder M, Schulz L, Löhr F, Gutfreund N, Finke F, Henrich E, Mezhyrova J, Lehnert R, Pampaloni F, Hummer G, Stelzer EHK, Knapp S, Dötsch V. p63 uses a switch-like mechanism to set the threshold for induction of apoptosis Nat Chem Biol. 2020 Oct;16(10):1078-1086._x000D_ 8: Agostinis P, Pinna LA, Meggio F, Marin O, Goris J, Vandenheede JR, Merlevede W. A synthetic peptide substrate specific for casein kinase I FEBS Lett. 1989 Dec 18;259(1):75-8._x000D_ 9: von Blume J, Knippschild U, Dequiedt F, Giamas G, Beck A, Auer A, Van Lint J, Adler G, Seufferlein T. Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2 EMBO J. 2007 Nov 14;26(22):4619-33._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17594292">10: Giamas G, Hirner H, Shoshiashvili L, Grothey A, Gessert S, Kühl M, Henne-Bruns D, Vorgias CE, Knippschild U. Phosphorylation of CK1delta: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivo Biochem J. 2007 Sep 15;406(3):389-98. </a>_x000D_ _x000D_ <strong>Products Related to CK1 Peptide Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>