Adropin (34-76) (human, mouse, rat)
Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway[1][2].
Product Specifications
CAS Number
1802086-30-1
UNSPSC
12352209
Target
Akt; Gli; JNK; PKA
Type
Peptides
Related Pathways
MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/adropin-34-76-human-mouse-rat.html
Purity
98.23
Solubility
DMSO : 100 mg/mL
Smiles
O=C(O)[C@H]1N(C([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC2=CC=C(C=C2)O)NC([C@H](CO)NC(CNC([C@H](CCC(O)=O)NC([C@H](CC3=CNC=N3)NC([C@H](CO)NC([C@H]4N(C([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@H]5N(C([C@H]6N(C([C@H]7N(C([C@H](C)NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@H]8N(C([C@H](CSSC[C@@H]9N)NC([C@H]%10N(C(CNC([C@H]%11N(C([C@H](CO)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H]%12N(C([C@H](CO)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CC%13=CNC=N%13)NC9=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC%12)=O)=O)=O)=O)CCC%11)=O)=O)CCC%10)=O)=O)CCC8)=O)=O)=O)=O)CCC7)=O)CCC6)=O)CCC5)=O)=O)=O)CCC4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1
Molecular Formula
C190H293N55O68S2
Molecular Weight
4499.82
References & Citations
[1]Gao S, et al. The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity. J Biol Chem. 2019 Sep 6;294 (36) :13366-13377.|[2]Liang M, et al. Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis. Sci Transl Med. 2024 Mar 27;16 (740) :eadd6570.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog