Quadrol

Quadrol is an immunostimulant that has been considered as a potentially useful active molecule for accelerating wound healing. Quadrol can form a complex with Ca2+, mediate the entry of Ca2+ into macrophages, and stimulate macrophage activation.

Product Specifications

CAS Number

[102-60-3]

Product Name Alternative

N, N, N′, N′-Tetrakis (2-hydroxypropyl) ethylenediamine; EDTP

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Quadrol.html

Concentration

10mM

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

CC(O)CN(CC(O)C)CCN(CC(O)C)CC(O)C

Molecular Formula

C14H32N2O4

Molecular Weight

292.41

Precautions

H302, H315, H319, H335

References & Citations

[1]Bhide MV, et al. In vitro stimulation of macrophages by quadrol [N, N, N', N'-tetrakis (2-hydroxypropyl) ethylenediamine]. J Immunopharmacol. 1985;7 (3) :303-12.|[2]Bhide MV, et al. Promotion of wound collagen formation in normal and diabetic mice by quadrol. Immunopharmacol Immunotoxicol. 1988;10 (4) :513-22.|[3]Bhide MV, et al. Investigation into the mechanism of stimulation of macrophages by Quadrol. Immunopharmacol Immunotoxicol. 1987;9 (1) :129-41.