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LY206130 (free base)

LY206130 free base is a 5-HT1A receptor antagonist with the activity of enhancing exogenous serotonin levels. LY206130 free base, when used concomitantly with fluoxetine, may enhance the appetite-suppressing effects of fluoxetine. LY206130 free base was shown to significantly reduce sweetened milk concentrate consumption in a dietary model. Clinical application of LY206130 free base may be beneficial in curbing eating disorders and obesity[1].

Product Specifications

CAS Number

127414-58-8

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly206130-free-base.html

Smiles

OC(CNC1CCCCC1)COC2=CC=CC3=C2C=CN3

Molecular Formula

C17H24N2O2

Molecular Weight

288.38

References & Citations

[1]5HT1A receptor antagonists enhance the functional activity of fluoxetine in a mouse model of feeding

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor

Frequently Asked Questions

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