Apoptosis inducer 20
Apoptosis inducer 20 (12) causes G2/M cell cycle arrest and induction of apoptosis via caspase 3/7 activation, which occurred during M arrest. Apoptosis inducer 20 is a novel indolic benzenesulfonamide with anti-proliferative effect against a broad panel of cancer cell lines, which is proming for research of new anti-mitotic agents[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-20.html
Smiles
CN1C=CC2=C1C=CC(N(CC#N)S(C3=CC(OC)=C(OC)C(OC)=C3)(=O)=O)=C2
Molecular Formula
C20H21N3O5S
Molecular Weight
415.46
References & Citations
[1]Fuentes-Martín R, et al. Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents[J]. Eur J Med Chem. 2024 Sep 5;275:116617.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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