Apoptosis inducer 20

Apoptosis inducer 20 (12) causes G2/M cell cycle arrest and induction of apoptosis via caspase 3/7 activation, which occurred during M arrest. Apoptosis inducer 20 is a novel indolic benzenesulfonamide with anti-proliferative effect against a broad panel of cancer cell lines, which is proming for research of new anti-mitotic agents[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/apoptosis-inducer-20.html

Smiles

CN1C=CC2=C1C=CC(N(CC#N)S(C3=CC(OC)=C(OC)C(OC)=C3)(=O)=O)=C2

Molecular Formula

C20H21N3O5S

Molecular Weight

415.46

References & Citations

[1]Fuentes-Martín R, et al. Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents[J]. Eur J Med Chem. 2024 Sep 5;275:116617.