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Zymosan A

Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury[1].

Product Specifications

CAS Number

58856-93-2

Product Name Alternative

Zymosan A from Saccharomyces cerevisiae

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Toll-like Receptor (TLR)

Type

Biochemical Assay Reagents

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zymosan-a.html

Solubility

DMSO : 1.94 mg/mL (ultrasonic; warming; adjust pH to 4 with HCl; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[ZymosanA]

Precautions

H315, H319, H335

References & Citations

[1]Du J, et al. Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2. Cell Death Dis. 2022 Oct 20;13 (10) :884. |[2]Monroe LL, et al. Zymosan-Induced Peritonitis: Effects on Cardiac Function, Temperature Regulation, Translocation of Bacteria, and Role of Dectin-1. Shock. 2016 Dec;46 (6) :723-730.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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