WAY-151932

WAY-151932 is a vasopressin V2-receptor agonist with IC50 of 80.3 nM and 778 nM in human-V2 binding and V1a binding assay.

Product Specifications

CAS Number

[220460-92-4]

Product Name Alternative

VNA-932; WAY-VNA 932

UNSPSC

12352005

Target

Vasopressin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/WAY-151932.html

Concentration

10mM

Purity

99.87

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(N2N=C(C)C=C2)C=C1Cl)N3CC4=CC=CN4CC5=CC=CC=C53

Molecular Formula

C23H19ClN4O

Molecular Weight

402.88

References & Citations

[1]Molinari AJ, et al. Identification and synthesis of major metabolites of Vasopressin V2-receptor agonist WAY-151932, and antagonist, Lixivaptan. Bioorg Med Chem Lett. 2007 Nov 1;17 (21) :5796-800.|[2]Failli AA, et al. Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists. Bioorg Med Chem Lett. 2006 Feb 15;16 (4) :954-9.