4-Methylumbelliferyl phosphate

4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant[1][2][3].

Product Specifications

CAS Number

[3368-04-5]

Product Name Alternative

4-MUP; MUP

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Phosphatase

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-Methylumbelliferyl_phosphate.html

Purity

99.96

Solubility

H2O : 17.5 mg/mL (ultrasonic)

Smiles

O=C1C=C(C)C2=CC=C(OP(O)(O)=O)C=C2O1

Molecular Formula

C10H9O6P

Molecular Weight

256.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Chambers JP, et al. Determination of serum acid phosphatase in Gaucher's disease using 4-methylumbelliferyl phosphate. Clin Chim Acta. 1977 Oct 1;80 (1) :67-77.|[2]Watanabe F, et al. The analysis of alkaline phosphatase isoenzyme using 4-methylumbelliferyl phosphate as substrate on a cellulose acetate membrane. Clin Chim Acta. 1979 Feb 1;91 (3) :273-6.|[3]Hao Chen, et al. Autonomic Molecular Transport for Ultrasensitive Surface-Enhanced Infrared Absorption Spectroscopy. ACS Appl. Polym. Mater. 2020, 2, 9, 3929-3935

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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