Dithiodipropionic acid
Dithiodipropionic acid can interact with CPUL1 (a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells[1].
Product Specifications
CAS Number
1119-62-6
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dithiodipropionic-acid.html
Concentration
10mM
Purity
99.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)CCSSCCC(O)=O
Molecular Formula
C6H10O4S2
Molecular Weight
210.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Jing Liu, et al. Nanoaggregates of Disulfide-Decorated TrxR Inhibitor Promote Cellular Uptake, Selective Targeting, and Antitumor Efficacy. Langmuir.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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