Lanuginosine
Lanuginosine is an alkaloid. Lanuginosine can be isolated from the stems of Xylopia laevigata (Annonaceae) and the leaves of Magnolia grandiflora. Lanuginosine induces Apoptosis. Lanuginosine inhibits AChE (IC50: 10.9 μM) . Lanuginosine inhibits Aβ aggregation. Lanuginosine exhibits anticancer activity against hepatocellular carcinoma, human promyelocytic leukemia, human chronic myeloid leukemia, melanoma, and brain tumors. Lanuginosine can be used in the research of Alzheimer's disease[1][2][3].
Product Specifications
CAS Number
[23740-25-2]
UNSPSC
12352005
Target
Amyloid-β; Apoptosis; Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Apoptosis; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lanuginosine.html
Purity
98.27
Solubility
DMSO : 0.5 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCl; heat to 60°C)
Smiles
O=C1C2=CC(OC)=CC=C2C3=C4OCOC4=CC5=CC=NC1=C53
Molecular Formula
C18H11NO4
Molecular Weight
305.28
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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