L-838417-d9
L-838417-d9 is the deuterium labeled L-838417. L-838417 is a subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
Product Specifications
CAS Number
1213669-91-0
UNSPSC
12352005
Target
GABA Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.71
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1N=CN=C1COC(C(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=C2)=NN3C2=NN=C3C4=CC(F)=CC=C4F
Molecular Formula
C19H10D9F2N7O
Molecular Weight
408.45
References & Citations
[1]Hofmann M, et al. Assessment of the effects of NS11394 and L-838417, α2/3 subunit-selective GABA (A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function [published correction appears in Behav Pharmacol. 2013 Apr;24 (2) :153]. Behav Pharmacol. 2012;23 (8) :790-801.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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