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L-838417-d9

L-838417-d9 is the deuterium labeled L-838417. L-838417 is a subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].

Product Specifications

CAS Number

1213669-91-0

UNSPSC

12352005

Target

GABA Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.71

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN1N=CN=C1COC(C(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=C2)=NN3C2=NN=C3C4=CC(F)=CC=C4F

Molecular Formula

C19H10D9F2N7O

Molecular Weight

408.45

References & Citations

[1]Hofmann M, et al. Assessment of the effects of NS11394 and L-838417, α2/3 subunit-selective GABA (A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function [published correction appears in Behav Pharmacol. 2013 Apr;24 (2) :153]. Behav Pharmacol. 2012;23 (8) :790-801.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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