Pelargonidin (chloride)

Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment[1][2][3].

Product Specifications

CAS Number

[134-04-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Quinone Reductase; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pelargonidin-chloride.html

Purity

99.10

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2=C(O)C=C3C(C=C(O)C=C3O)=[O+]2)C=C1.[Cl-]

Molecular Formula

C15H11ClO5

Molecular Weight

306.70

Precautions

H302, H315, H319

References & Citations

[1]S A van Acke, et al. Flavonoids as Scavengers of Nitric Oxide Radical.Biochem Biophys Res Commun. 1995 Sep 25;214 (3) :755-9.|[2]Soleimani Asl S, et al. Pelargonidin exhibits restoring effects against amyloid β-induced deficits in the hippocampus of male rats. Med J Islam Repub Iran. 2019 Dec 12;33:135. |[3]Li S, et al. Pelargonidin reduces the TPA induced transformation of mouse epidermal cells -potential involvement of Nrf2 promoter demethylation. Chem Biol Interact. 2019 Aug 25;309:108701.