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Poloxamer 122 (L42)

Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering[1][2].

Product Specifications

CAS Number

9003-11-6

Product Name Alternative

PEG-PPG-PEG, 1630 (Average)

UNSPSC

12352200

Target

Bacterial; Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/poloxamer-122-l42.html

Solubility

10 mM in DMSO

Smiles

[Poloxamer122(L42)]

Molecular Weight

1630 (Average)

References & Citations

[1]Singh-Joy SD, et al., Safety assessment of poloxamers 101, 105, 108, 122, 123, 124, 181, 182, 183, 184, 185, 188, 212, 215, 217, 231, 234, 235, 237, 238, 282, 284, 288, 331, 333, 334, 335, 338, 401, 402, 403, and 407, poloxamer 105 benzoate, and poloxamer 182 dibenzoate as used in cosmetics. Int J Toxicol. 2008;27 Suppl 2:93-128.|[2]Hunter RL, et al., Enhancement of antibiotic susceptibility and suppression of Mycobacterium avium complex growth by poloxamer 331. antimicrob Agents Chemother. 1995 Feb;39 (2) :435-9.

Shipping Conditions

Room temperature

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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