Epigen (Human, Recombinant, Highly Pure)

<strong>Epigen (Human, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010277_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Epigen (Human, Recombinant) expressed in CHO cells. This protein acts as an EGF-like growth factor with mitogenic effects on cells expressing ErbB-1._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuEpigen; Epithelial mitogen; EPG_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Verduci L, Strano S, Yarden Y, Blandino G. The circRNA-microRNA code:_x000D_ emerging implications for cancer diagnosis and treatment. Mol Oncol. 2019_x000D_ Apr;13(4):669-680._x000D_ _x000D_ 2: Roskoski R Jr. The ErbB/HER family of protein-tyrosine kinases and cancer._x000D_ Pharmacol Res. 2014 Jan;79:34-74._x000D_ _x000D_ 3: Kleibl Z, Kristensen VN. Women at high risk of breast cancer: Molecular_x000D_ characteristics, clinical presentation and management. Breast. 2016_x000D_ Aug;28:136-44._x000D_ _x000D_ 4: Nordengen K, Kirsebom BE, Henjum K, Selnes P, Gísladóttir B, Wettergreen M,_x000D_ Torsetnes SB, Grøntvedt GR, Waterloo KK, Aarsland D, Nilsson LNG, Fladby T._x000D_ Glial activation and inflammation along the Alzheimer's disease continuum. J_x000D_ Neuroinflammation. 2019 Feb 21;16(1):46._x000D_ _x000D_ 5: Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK,_x000D_ Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein_x000D_ G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN,_x000D_ Mills GB, Pradeep S, Chaluvally-Raghavan P. miRNA551b-3p Activates an Oncostatin_x000D_ Signaling Module for the Progression of Triple-Negative Breast Cancer. Cell Rep._x000D_ 2019 Dec 24;29(13):4389-4406.e10._x000D_ _x000D_ 6: Rayego-Mateos S, Rodrigues-Diez R, Morgado-Pascual JL, Valentijn F,_x000D_ Valdivielso JM, Goldschmeding R, Ruiz-Ortega M. Role of Epidermal Growth Factor_x000D_ Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage. Mediators_x000D_ Inflamm. 2018 Dec 23;2018:8739473._x000D_ _x000D_ 7: Lautrup S, Caponio D, Cheung HH, Piccoli C, Stevnsner T, Chan WY, Fang EF._x000D_ Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging_x000D_ and age-related diseases. Biogerontology. 2019 Jun;20(3):255-269._x000D_ _x000D_ 8: Verduci L, Ferraiuolo M, Sacconi A, Ganci F, Vitale J, Colombo T, Paci P,_x000D_ Strano S, Macino G, Rajewsky N, Blandino G. The oncogenic role of circPVT1 in_x000D_ head and neck squamous cell carcinoma is mediated through the mutant_x000D_ p53/YAP/TEAD transcription-competent complex. Genome Biol. 2017 Dec_x000D_ 20;18(1):237._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31181813/">9: Pellecchia S, Sepe R, Federico A, Cuomo M, Credendino SC, Pisapia P,_x000D_ Bellevicine C, Nicolau-Neto P, Severo Ramundo M, Crescenzi E, De Vita G,_x000D_ Terracciano LM, Chiariotti L, Fusco A, Pallante P. The_x000D_ <i>Metallophosphoesterase-Domain-Containing Protein 2</i> (<i>MPPED2</i>) Gene_x000D_ Acts as Tumor Suppressor in Breast Cancer. Cancers (Basel). 2019 Jun_x000D_ 8;11(6):797. </a>_x000D_ _x000D_ <strong>Products Related to Epigen (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>