Icariside E4
Product Specifications
UNSPSC Description
Icariside E4 is an antinociceptive agent, and can be isolated from Tabebuia roseo-alba. Icariside E4 has peripheral analgesic activity by ATP-sensitive K+ channel-dependent mechanisms. Icariside E4 also has anti-oxidant, anti-Alzheimer and anti-inflammatory effects[1][2].
Target Antigen
Potassium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/icariside-e4.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1C2=CC(CCCO)=CC(OC)=C2O[C@@]1([H])C3=CC(OC)=C(C=C3)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O
Molecular Weight
506.54
References & Citations
[1]Veiga TA, et al. Furoquinoline alkaloids isolated from Balfourodendron riedelianum as photosynthetic inhibitors in spinach chloroplasts. J Photochem Photobiol B. 2013 Mar 5;120:36-43.|[2]Suh JY, et al. Hypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells. Phytother Res. 2023 Jan;37(1):7-14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N9854/Icariside-E4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N9854/
Clinical Information
No Development Reported
CAS Number
126253-42-7
Available Sizes
Curated Selection
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