Ent-Prostaglandin E2

Ent-Prostaglandin E2 (ent-PGE2) is an enantiomer of PGE2 (HY-101952) . unlike PGE2, ent-PGE2 is a poor substrate for 15-hydroxyprostaglandin dehydrogenase[1].

Product Specifications

CAS Number

[65085-69-0]

Product Name Alternative

Ent-PGE2

UNSPSC

12352211

Hazard Statement

H225-H319-H336

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/ent-prostaglandin-e2.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@H]([C@@H]([C@H](C1)O)/C=C/[C@@H](CCCCC)O)C/C=C\CCCC(O)=O

Molecular Formula

C20H32O5

Molecular Weight

352.47

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Gao L, et al. Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase. J Biol Chem. 2003 Aug 1;278 (31) :28479-89.