IDO/TDO-IN-1
IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1].
Product Specifications
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido-tdo-in-1.html
Purity
99.30
Solubility
DMSO : 30 mg/mL (ultrasonic; adjust pH to 2 with HCl)
Smiles
CN1N=CC(C2=CC=C(N3CCC([C@@H](C4=C5C=CC=C4F)N6C5=CN=C6)CC3)C=C2)=C1
Molecular Formula
C25H24FN5
Molecular Weight
413.49
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128355/IDO-TDO-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128355/IDO-TDO-IN-1-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[2033173-01-0]
Available Sizes
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