Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

IDO/TDO-IN-1

IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1].

Product Specifications

CAS Number

2033173-01-0

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ido-tdo-in-1.html

Purity

99.30

Solubility

DMSO : 30 mg/mL (ultrasonic; adjust pH to 2 with HCl)

Smiles

CN1N=CC(C2=CC=C(N3CCC([C@@H](C4=C5C=CC=C4F)N6C5=CN=C6)CC3)C=C2)=C1

Molecular Formula

C25H24FN5

Molecular Weight

413.49

References & Citations

[1]Tu W, et al. Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors. ACS Med Chem Lett. 2019 Jun 3;10 (6) :949-953.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Plastin L Recombinant Rabbit Monoclonal Antibody [JE48-95]
ET7109-87 100 µL

Plastin L Recombinant Rabbit Monoclonal Antibody [JE48-95]

Sign In for Pricing
View Details
Adipophilin / Perilipin-2 (Marker of Lipid Accumulation) (ADFP/2755R), CF647 conjugate, 0.1mg/mL
BNC472755-100 1x 100 µL

Adipophilin / Perilipin-2 (Marker of Lipid Accumulation) (ADFP/2755R), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Human HBEGF Antibody Pair Set
E-KAB-0428 50 µL & 100 µg

Human HBEGF Antibody Pair Set

Sign In for Pricing
View Details
FRY Human Gene Knockout Kit (CRISPR)
KN420587 1 Kit

FRY Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) (IGHM/2557R), 0.2mg/mL
BNUB2557-100 1x 100 µL

Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) (IGHM/2557R), 0.2mg/mL

Sign In for Pricing
View Details
EY-20 Reagent Tubes
13-020-50 1 Each

EY-20 Reagent Tubes

Sign In for Pricing
View Details