2-MNG
Product Specifications
UNSPSC Description
2-MNG (2-Mercaptonicotinoyl glycine) is an inhibitor for melanogenesis with an average IC50 of 49.5μM in normal human melanocytes. 2-MNG binds to melanin precursors, prevents the incorporation into growing melanin, and thereby inhibits the synthesis of eumelanin and pheomelanin. 2-MNG can be used in research about skin pigmentation[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-mng.html
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
O=C(O)CNC(C1=CC=CNC1=S)=O
Molecular Weight
212.23
References & Citations
[1]Sextius P, et al., 2-Mercaptonicotinoyl glycine, a new potent melanogenesis inhibitor, exhibits a unique mode of action while preserving melanocyte integrity. Pigment Cell Melanoma Res. 2024 Jul;37(4):462-479.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159107/2-MNG-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159107/2-MNG-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2101538-28-5
Available Sizes
Curated Selection
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