Tisotumab
Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody and ADC antibody. Tisotumab targets tissue factor (TF) . Tisotumab can be used to synthesize antibody-drug conjugates (ADCs) targeting tissue factor (TF), Tisotumab vedotin (HY-152963) . Tisotumab can be used for the research of solid tumors[1].
Product Specifications
CAS Number
[1418628-81-5]
Product Name Alternative
Anti-Human F3 Recombinant Antibody
UNSPSC
12352203
Target
ADC Antibody
Type
Inhibitory Antibodies
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tisotumab.html
Purity
99.33
Solubility
10 mM in DMSO
Smiles
[Tisotumab]
Molecular Weight
(144.66 kDa)
References & Citations
[1]Coleman RL, et al. Efficacy and safety of tisotumab vedotin in previously treated recurrent or metastatic cervical cancer (innovaTV 204/GOG-3023/ENGOT-cx6) : a multicentre, open-label, single-arm, phase 2 study. Lancet Oncol. 2021 May;22 (5) :609-619.|[2]Takao S, et al. Tissue factor targeted near-infrared photoimmunotherapy: a versatile therapeutic approach for malignancies. Cancer Immunol Immunother. 2025 Jan 3;74 (2) :48.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
Curated Selection
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