Idazoxan
Idazoxan (RX 781094) is a potent antagonist of α2 adrenergic receptor (α2AR) and potential I2 imidazoline receptor agonist. Idazoxan can be used in the research of antidepression and schizophrenia. Idazoxan has oral bioactivity[1].
Product Specifications
CAS Number
[79944-58-4]
Product Name Alternative
RX 781094
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adrenergic Receptor; Imidazoline Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/idazoxan.html
Smiles
C1(OCC(C2=NCCN2)O3)=C3C=CC=C1
Molecular Formula
C11H12N2O2
Molecular Weight
204.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]H Dabiré. Idazoxan: a novel pharmacological tool for the study of alpha 2-adrenoceptors. J Pharmacol. 1986 Apr-Jun;17 (2) :113-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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