RBC6
RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines[1].
Product Specifications
CAS Number
[381186-64-7]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rbc6.html
Purity
98.88
Solubility
DMSO : 50 mg/mL
Smiles
N#CC(C1C2=CC(Cl)=CC(Cl)=C2O)=C(N)OC3=C1C(CCC)=NN3
Molecular Formula
C16H14Cl2N4O2
Molecular Weight
365.21
References & Citations
[1]Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014 Nov 20;515 (7527) :443-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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