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RBC6

RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines[1].

Product Specifications

CAS Number

[381186-64-7]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rbc6.html

Purity

98.88

Solubility

DMSO : 50 mg/mL

Smiles

N#CC(C1C2=CC(Cl)=CC(Cl)=C2O)=C(N)OC3=C1C(CCC)=NN3

Molecular Formula

C16H14Cl2N4O2

Molecular Weight

365.21

References & Citations

[1]Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014 Nov 20;515 (7527) :443-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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