Amino-PEG2-C2-acid
Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG2-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[791028-27-8]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg2-c2-acid.html
Purity
99.72
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CCOCCOCCN
Molecular Formula
C7H15NO4
Molecular Weight
177.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof. WO2016197946A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
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