FR-188582
FR-188582 is a highly selective inhibitor of cyclooxygenase (COX) -2, with an IC50 value of 17 nM.
Product Specifications
CAS Number
[189699-82-9]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/FR-188582.html
Purity
99.12
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C2=CC(Cl)=NN2C3=CC=CC=C3)C=C1)(C)=O
Molecular Formula
C16H13ClN2O2S
Molecular Weight
332.80
References & Citations
[1]Ochi T, et al. The anti-inflammatory effect of FR188582, a highly selective inhibitor of cyclooxygenase-2, with an ulcerogenic sparing effect in rats. Jpn J Pharmacol. 2001 Feb;85 (2) :175-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
Available Sizes
Curated Selection
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