Diazolidinyl urea

Diazolidinyl urea is a broad-spectrum preservative commonly used in cosmetics. Diazolidinyl urea exerts antibacterial effects by decomposing and releasing formaldehyde. Diazolidinyl urea is effective against most contaminating microorganisms, especially Pseudomonas[1][2][3].

Product Specifications

CAS Number

[78491-02-8]

UNSPSC

12352005

Hazard Statement

H317

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/diazolidinyl-urea.html

Purity

95.0

Solubility

DMSO : 250 mg/mL (ultrasonic) |H2O : 166.67 mg/mL (ultrasonic)

Smiles

O=C(NCO)N(C(C(N1CO)=O)N(CO)C1=O)CO

Molecular Formula

C8H14N4O7

Molecular Weight

278.22

Precautions

H317

References & Citations

[1]Kantor GR, et al. Acute allergic contact dermatitis from diazolidinyl urea (Germall II) in a hair gel. J Am Acad Dermatol. 1985;13 (1) :116-119.|[2]Doi T, et al. The different decomposition properties of diazolidinyl urea in cosmetics and patch test materials. Contact Dermatitis. 2011;65 (2) :81-91.|[3]Llabres CM, et al. Antimicrobial activities of N-chloramines and diazolidinyl urea. Appl Environ Microbiol. 1985 Feb;49 (2) :370-3.