UCT943
Product Specifications
UNSPSC Description
UCT943 is a next-generation Plasmodium falciparum PI4K inhibitor. UCT943 inhibits the P. vivax PI4K (PvPI4K) enzyme with an IC50 of 23 nM[1].
Target Antigen
Parasite; PI4K
Type
Reference compound
Related Pathways
Anti-infection;PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/UCT943.html
Purity
99.08
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
FC(F)(F)C1=CC=C(C2=NC(C3=CC=C(C(N4CCNCC4)=O)C=C3)=CN=C2N)C=C1
Molecular Weight
427.42
References & Citations
[1]Brunschwig C, et al. UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria. Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00012-18.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112435/UCT943-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112435/UCT943-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1450666-80-4
Available Sizes
Curated Selection
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