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AEBSF (hydrochloride)

Product Specifications

UNSPSC Description

AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.

Target Antigen

Influenza Virus; Ser/Thr Protease; Thrombin

Type

Reference compound

Related Pathways

Anti-infection;Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/AEBSF.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL

Smiles

O=S(C1=CC=C(CCN)C=C1)(F)=O.[H]Cl

Molecular Weight

239.69

References & Citations

[1]Citron M, et al. Inhibition of amyloid beta-protein production in neural cells by the serine protease inhibitor AEBSF. Neuron. 1996 Jul;17(1):171-9|[2]Nakabo Y, et al. Lysis of leukemic cells by human macrophages: inhibition by 4-(2-aminoethyl)-benzenesulfonyl fluoride (AEBSF), a serine protease inhibitor. J Leukoc Biol. 1996 Sep;60(3):328-36.|[3]Buitrago-Rey R, et al. Evaluation of two inhibitors of invasion: LY311727 [3-(3-acetamide-1-benzyl-2-ethyl-indolyl-5-oxy)propane phosphonic acid] and AEBSF [4-(2-aminoethyl)-benzenesulphonyl fluoride] in acute murine toxoplasmosis. J Antimicrob Chemother.|[4]Jiang YH, et al. Serine protease inhibitor 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF) inhibits the rat embryo implantation in vivo and interferes with cell adhesion in vitro. Contraception. 2011 Dec;84(6):642-8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12821/AEBSF-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12821/AEBSF-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

30827-99-7

Available Sizes

Curated Selection

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