CDK8-IN-14
Product Specifications
UNSPSC Description
CDK8-IN-14 (compound 12) inhibits CDK8 with an IC50 value of 39.2 nM and has anti-AML cell proliferation activity (molm-13 GC50 = 0.02±0.01μM, MV4-11 GC50 = 0.03±0.01μM)[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/cdk8-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C(N)C1=CC=CC(C2=CN=C(NC=C3C4=COC=C4)C3=C2)=C1
Molecular Weight
303.31
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162293/CDK8-IN-14-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162293/
Clinical Information
No Development Reported
CAS Number
2924193-12-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NBP2-81082AF594 0.1 mL
Rabbit Monoclonal TGF-alpha Antibody (tAb2) [Alexa Fluor 594]
Ask
View Details PIP1194 4800 Pack
Axygen 200uL MultiRackNatural Pipette Tip TipSta S 960/stck 5 stck/cs
Ask
View Details