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VCC972839:01

VCC972839:01 is an inhibitor for cyclin dependent kinase (CDK9), with IC50 of 7 nM. VCC972839:01 inhibits the cell viability of SCLC cells in nanomolar levels. VCC972839:01 induces apoptosis through an intrinsic pathway. VCC972839:01 exhibits antitumor activity in mouse model[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; CDK

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vcc972839-01.html

Smiles

COC1=CC=CC=C1C2=NC=NC(NC3=CC(CN4C=NC5=C4C=CC=C5)=CC=C3)=N2

Molecular Formula

C24H20N6O

Molecular Weight

408.46

References & Citations

[1]Valdez Capuccino L, et al., CDK9 inhibition as an effective therapy for small cell lung cancer. Cell Death Dis. 2024 May 20;15 (5) :345.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK9

Frequently Asked Questions

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