Atropine methyl (bromide)

Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine[1][2].

Product Specifications

CAS Number

[2870-71-5]

Product Name Alternative

Methylatropine (bromide)

UNSPSC

12352005

Hazard Statement

H302

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Atropine_methyl_bromide.html

Purity

99.81

Solubility

DMSO : 147.06 mg/mL (ultrasonic)

Smiles

C[N+]1([C@H]2C[C@H](OC(C(C3=CC=CC=C3)CO)=O)C[C@@H]1CC2)C.[Br-]

Molecular Formula

C18H26BrNO3

Molecular Weight

384.31

Precautions

H302

References & Citations

[1]Methylatropine.|[2]Nurminen ML, et al. Central inhibition of nitric oxide synthesis increases blood pressure and heart rate in anesthetized rats. Methods Find Exp Clin Pharmacol. 1997 Jan-Feb;19 (1) :35-41.