1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction[1][2].
Product Specifications
CAS Number
[89576-29-4]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H331, H336, H351, H372
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/1-oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine.html
Purity
99.0
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)COP(OCCN)(O)=O)=O
Molecular Formula
C23H46NO7P
Molecular Weight
479.59
Precautions
H302, H315, H319, H331, H336, H351, H372
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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