Edivoxetine (hydrochloride)
Edivoxetine (LY 2216684) hydrochloride is a potent and selective norepinephrine reuptake inhibitor. Edivoxetine hydrochloride can be used for the study of major depressive disorder (MDD) and attention-deficit/hyperactivity disorder (ADHD) [1][2].
Product Specifications
CAS Number
1194374-05-4
Product Name Alternative
LY 2216684 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H318, H336, H373, H412
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/edivoxetine-hydrochloride.html
Purity
99.85
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC(C=CC(F)=C1)=C1C[C@@](C2CCOCC2)([C@]3([H])CNCCO3)O.Cl
Molecular Formula
C18H27ClFNO4
Molecular Weight
375.86
Precautions
H302, H318, H336, H373, H412
References & Citations
[1]Jin L, et al. Clinical outcomes from an opeJin L, Xu W, Krefetz D, et al. Clinical outcomes from an open-label study of edivoxetine use in pediatric patients with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2013;23 (3) :200-207|[2]Kielbasa W, et al. The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor. Eur J Clin Pharmacol. 2013;69 (12) :2011-2019.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
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