Edivoxetine (hydrochloride)

Edivoxetine (LY 2216684) hydrochloride is a potent and selective norepinephrine reuptake inhibitor. Edivoxetine hydrochloride can be used for the study of major depressive disorder (MDD) and attention-deficit/hyperactivity disorder (ADHD) [1][2].

Product Specifications

CAS Number

[1194374-05-4]

Product Name Alternative

LY 2216684 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H318, H336, H373, H412

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/edivoxetine-hydrochloride.html

Purity

99.85

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC(C=CC(F)=C1)=C1C[C@@](C2CCOCC2)([C@]3([H])CNCCO3)O.Cl

Molecular Formula

C18H27ClFNO4

Molecular Weight

375.86

Precautions

H302, H318, H336, H373, H412

References & Citations

[1]Jin L, et al. Clinical outcomes from an opeJin L, Xu W, Krefetz D, et al. Clinical outcomes from an open-label study of edivoxetine use in pediatric patients with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2013;23 (3) :200-207|[2]Kielbasa W, et al. The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor. Eur J Clin Pharmacol. 2013;69 (12) :2011-2019.