Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Endo-BCN-PEG4-Val-Cit-PAB-MMAE

Endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker conjugated with drug containing 4-unit PEG, which can be used for synthesizing antibody-drug conjugates (ADCs) . endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1].

Product Specifications

CAS Number

[2762519-08-2]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Drug-Linker Conjugates for ADC

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/endo-bcn-peg4-val-cit-pab-mmae.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC[C@@H]([C@H](N(C([C@@H](NC([C@@H](N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCNC(OC[C@@H]2[C@@]3([H])[C@]2([H])CCC#CCC3)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O)C)C(C)C)=O)C(C)C)=O)C)[C@H](OC)CC(N4CCC[C@H]4[C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C5=CC=CC=C5)C)=O)C)=O)C

Molecular Formula

C80H127N11O19

Molecular Weight

1546.93

Precautions

H302, H315, H319, H335

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

Zmym4 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4878202 1.0 µg DNA

Zmym4 sgRNA CRISPR Lentivector (Mouse) (Target 1)

Sign In for Pricing

Recombinant Monkeypox Virus Protein, Toll/IL1-receptor [TIR]-like Protein

MPXV-0864 100 µg

Recombinant Monkeypox Virus Protein, Toll/IL1-receptor [TIR]-like Protein

Sign In for Pricing

PTPRS Protein Vector (Human) (pPB-C-His)

PV033657 500 ng

PTPRS Protein Vector (Human) (pPB-C-His)

Sign In for Pricing

ACSM4 (NM_001080454) Human Tagged ORF Clone

RG213310 10 µg

ACSM4 (NM_001080454) Human Tagged ORF Clone

Sign In for Pricing

Rat Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) ELISA Kit

abx255585-01 96 Tests

Rat Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) ELISA Kit

Sign In for Pricing

Rat Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) ELISA Kit

abx255585-02 5x 96 Tests

Rat Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) ELISA Kit

Sign In for Pricing