Selenomethionine

Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity[1][2][3].

Product Specifications

CAS Number

[1464-42-2]

Product Name Alternative

Seleno-DL-methionine; DL-Selenomethionine

UNSPSC

12352211

Hazard Statement

H301+H331, H373, H410

Target

Autophagy; Keap1-Nrf2

Type

Natural Products

Related Pathways

Autophagy; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Selenomethionine.html

Purity

99.86

Solubility

H2O : 12.5 mg/mL (ultrasonic)

Smiles

O=C(O)C(N)CC[Se]C

Molecular Formula

C5H11NO2Se

Molecular Weight

196.11

Precautions

H301+H331, H373, H410

References & Citations

[1]Kupsco A, et al. Mechanisms of selenomethionine developmental toxicity and the impacts of combined hypersaline conditions on Japanese medaka (Oryzias latipes) . Environ Sci Technol. 2014 Jun 17;48 (12) :7062-8.|[2]Redman C, et al. Inhibitory effect of selenomethionine on the growth of three selected human tumor cell lines. Cancer Lett. 1998 Mar 13;125 (1-2) :103-10.|[3]Wang P, et al. Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2. Oxid Med Cell Longev. 2022 Apr 11;2022:7531788.