WLB-87848
WLB-87848 is a selective, orally active, and blood-brain barrier (BBB) permeable σ1 receptor agonist with the Ki of 9 nM. WLB-87848 rescues recognition memory impairment[1].
Product Specifications
CAS Number
[2839205-09-1]
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/wlb-87848.html
Smiles
FC(C=CC([C@H](N1C=NC(SC2=C3CCNC2)=C3C1=O)C)=C4)=C4F
Molecular Formula
C17H15F2N3OS
Molecular Weight
347.38
References & Citations
[1]Christmann U, et al. WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity. J Med Chem. 2024;67 (11) :9150-9164.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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