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WLB-87848

WLB-87848 is a selective, orally active, and blood-brain barrier (BBB) permeable σ1 receptor agonist with the Ki of 9 nM. WLB-87848 rescues recognition memory impairment[1].

Product Specifications

CAS Number

2839205-09-1

UNSPSC

12352005

Target

Sigma Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/wlb-87848.html

Smiles

FC(C=CC([C@H](N1C=NC(SC2=C3CCNC2)=C3C1=O)C)=C4)=C4F

Molecular Formula

C17H15F2N3OS

Molecular Weight

347.38

References & Citations

[1]Christmann U, et al. WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity. J Med Chem. 2024;67 (11) :9150-9164.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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