Seselin

Seselin is an anticancer, antinociceptive, anti-inflammatory and antifungal agent. Seselin is orally active[1][2][3].

Product Specifications

CAS Number

[523-59-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/seselin.html

Purity

99.55

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1(C=CC2=C(O1)C=CC3=C2OC(=O)C=C3)C

Molecular Formula

C14H12O3

Molecular Weight

228.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Chou HC, et al. Cytotoxic and anti-platelet aggregation constituents from the root wood of Melicope semecarpifolia. Planta Med. 2005 Nov;71 (11) :1078-81.|[2]Lima V, et al. Antinociceptive activity of the pyranocoumarin seselin in mice. Fitoterapia. 2006 Dec;77 (7-8) :574-8.Lima V, et al. Antinociceptive activity of the pyranocoumarin seselin in mice. Fitoterapia. 2006 Dec;77 (7-8) :574-8.Lima V, et al. Antinociceptive activity of the pyranocoumarin seselin in mice. Fitoterapia. 2006 Dec;77 (7-8) :574-8.|[3]Feng L, et al. Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages. Br J Pharmacol. 2019 Jan;176 (2) :317-333.