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(2S,4R) -Fmoc-L-Pro (4-N3) -OH

(2S,4R) -Fmoc-L-Pro (4-N3) -OH is a click chemistry reagent containing an azide[1]. (2S,4R) -Fmoc-L-Pro (4-N3) -OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[702679-55-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2s-4r-fmoc-l-pro-4-n3-oh.html

Purity

98.67

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](C[C@H](C1)N=[N+]=[N-])C(O)=O)OCC2C3=CC=CC=C3C4=CC=CC=C42

Molecular Formula

C20H18N4O4

Molecular Weight

378.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Lewandowska U, et al. Hierarchical supramolecular assembly of sterically demanding π-systems by conjugation with oligoprolines. Angew Chem Int Ed Engl. 2014 Nov 10;53 (46) :12537-41. doi: 10.1002/anie.201408279. Epub 2014 Oct 10.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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