Centhaquin
Centhaquine (Centhaquin; PMZ-2010) is a novel agent has the potential for treatment of haemorrhagic shock. Centhaquine (Centhaquin; PMZ-2010) can augment cardiac output, reduce systemic vascular resistance in haemorrhagic models[1][2].
Product Specifications
CAS Number
57961-90-7
Product Name Alternative
Centhaquine; PMZ-2010
UNSPSC
12352005
Hazard Statement
H315, H319, H413
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/centhaquin.html
Purity
99.93
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
CC1=CC=CC(N(CC2)CCN2CCC3=NC4=C(C=CC=C4)C=C3)=C1
Molecular Formula
C22H25N3
Molecular Weight
331.45
Precautions
H315, H319, H413
References & Citations
[1]Srimal RC, et al. Pharmacological studies on 2- (2- (4- (3-methylphenyl) -1-piperazinyl) ethyl) quinoline (centhaquin) . I. Hypotensive activity.Pharmacol Res. 1990 May-Jun;22 (3) :319-29.|[2]Papalexopoulou K, et al. Centhaquin Effects in a Swine Model of Ventricular Fibrillation: Centhaquin and Cardiac Arrest.Heart Lung Circ. 2017 Aug;26 (8) :856-863.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Available Sizes
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