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(D-Met2, Pro5) -Enkephalinamide

(D-Met2, Pro5) -Enkephalinamide is a highly potent opiate agonist, and shows antinociceptive activity[1][2][3].

Product Specifications

CAS Number

63307-63-1

UNSPSC

12352209

Target

Opioid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/d-met2-pro5-enkephalinamide.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H](CCSC)C(NCC(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N)=O)=O)=O)=O)[C@H](CC3=CC=C(C=C3)O)N

Molecular Formula

C30H40N6O6S

Molecular Weight

612.74

References & Citations

[1]Decsi L, et al. Effect of (D-Met2, Pro5) enkephalinamide, a highly potent opiate agonist, on the drinking behaviour of rats. Neuropharmacology. 1985 Jan;24 (1) :5-8.|[2]Nagy G, et al. (D-Met2, Pro5) enkephalinamide causes a decrease in plasma prolactin levels of lactating rats continuously suckled and an increase in those deprived of their litter. Regul Pept. 1984 Jul;8 (4) :321-6.|[3]Wollemann M, et al. Effect of Met-enkephalin and (D-Met2, Pro5) -enkephalinamide on the adenylate cyclase activity of rat brain. Neurochem Res. 1979 Oct;4 (5) :627-31.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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