Pyridoxal 5'-phosphate (monohydrate)
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) [1][2].
Product Specifications
CAS Number
[41468-25-1]
Product Name Alternative
Pyridoxal phosphate (monohydrate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β; Endogenous Metabolite; ERK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pyridoxal-5-phosphate-monohydrate.html
Concentration
10mM
Purity
99.38
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 6.25 mg/mL (ultrasonic)
Smiles
O=CC1=C(O)C(C)=NC=C1COP(O)(O)=O.[H]O[H]
Molecular Formula
C8H12NO7P
Molecular Weight
265.16
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Citation 01
Int J Biol Macromol. 2025 Jul 21;320 (Pt 4) :146219.|Nat Immunol. 2023 Jan;24 (1) :162-173.|J Agric Food Chem. 2025 Oct 15;73 (41) :25991-25997.
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