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MMP-7-IN-1

Product Specifications

UNSPSC Description

MMP-7-IN-1 is a potent and selective inhibitor of MMP-7 over MMP-1, -2, -3, -8, -9, -13 with an IC50 value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis[1].

Target Antigen

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmp-7-in-1.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=CC=C(C=C1C(F)(F)F)S(N[C@@H](CCC(NCC(N[C@H](C(N[C@H](C(N2CCC[C@H]2CC(N)=O)=O)C(C)C)=O)CC(C)C)=O)=O)C(O)=O)(=O)=O

Molecular Weight

769.23

References & Citations

[1]Tabuse H, et al. Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1' Subsite Binder with Short Peptides. J Med Chem. 2022 Oct 13;65(19):13253-13263.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-151540/MMP-7-IN-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-151540/MMP-7-IN-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2865097-05-6

Available Sizes

Curated Selection

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