MMP-7-IN-1
Product Specifications
UNSPSC Description
MMP-7-IN-1 is a potent and selective inhibitor of MMP-7 over MMP-1, -2, -3, -8, -9, -13 with an IC50 value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis[1].
Target Antigen
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmp-7-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(C=C1C(F)(F)F)S(N[C@@H](CCC(NCC(N[C@H](C(N[C@H](C(N2CCC[C@H]2CC(N)=O)=O)C(C)C)=O)CC(C)C)=O)=O)C(O)=O)(=O)=O
Molecular Weight
769.23
References & Citations
[1]Tabuse H, et al. Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1' Subsite Binder with Short Peptides. J Med Chem. 2022 Oct 13;65(19):13253-13263.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151540/MMP-7-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151540/MMP-7-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2865097-05-6
Available Sizes
Curated Selection
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