Recombinant Human Interleukin-17A protein (IL17A) (Active)
Product Specifications
Background
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1, intracellular adhesion molecule 1 in fibroblasts.
Product Name Alternative
IL-17, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8
Gene ID
3605
UniProt
Q16552
Target
GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VA
Purification
>95% as determined by SDS-PAGE and HPLC.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH,3T3 cells is less than 7.5 ng, ml, corresponding to a specific activity of 1.3 105 IU, mg.
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Calculated Molecular Weight
31.0 kDa
Formulation
0.2 ?m filtered PBS, pH 7.4 , lyophilized
Host or Source
E.Coli
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