SGA360
SGA360 suppress inflammatory SAA1 signaling in an AHR-dependent manner through a mechanism that does not require AHR binding to its cognate response element (partial antagonist) [1].
Product Specifications
CAS Number
680611-86-3
UNSPSC
12352005
Target
Apolipoprotein
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sga360.html
Purity
99.93
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
C=CCN1N=C(C2=CC=CC(C(F)(F)F)=C21)C3=CC=C(C=C3OC)OC
Molecular Formula
C19H17F3N2O2
Molecular Weight
362.35
References & Citations
[1]Iain A Murray, et al. Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties. Chem Res Toxicol. 2010 May 17;23 (5) :955-66.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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