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SGA360

SGA360 suppress inflammatory SAA1 signaling in an AHR-dependent manner through a mechanism that does not require AHR binding to its cognate response element (partial antagonist) [1].

Product Specifications

CAS Number

680611-86-3

UNSPSC

12352005

Target

Apolipoprotein

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sga360.html

Purity

99.93

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

C=CCN1N=C(C2=CC=CC(C(F)(F)F)=C21)C3=CC=C(C=C3OC)OC

Molecular Formula

C19H17F3N2O2

Molecular Weight

362.35

References & Citations

[1]Iain A Murray, et al. Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties. Chem Res Toxicol. 2010 May 17;23 (5) :955-66.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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